HTLV-1 infection and the viral etiology of multiple sclerosis.

Assessment of HTLV-I proviral load, HIV viral load and CD4 T cell count in infected subjects; with an emphasis on viral replication in co-infection

  Objective(s): HTLV-I and HIV virus quantification is an important marker for assessment of virus activities. Since there is a direct relationship between the number of virus and disease progression, HTLV- I and HIV co-infection might have an influence on the development of viral associated diseases, thus, viral replication of these viruses and co-infection were evaluated.   Materials and...

Muscle damage induced by isotretinoin.

The absence of antibody to HTLV-I and HIV in patients with multiple sclerosis from France and similar findings in Italian patients (L ChiecoBianchi et al, personal communication) argue against these viruses having a role in the development of multiple sclerosis. Furthermore, the negative results in patients from the French West Indies, an area endemic for HTLV-I, strengthen the lack of a serolo...

Human T Lymphotropic Virus Type I (HTLV-I) Oncogenesis: Molecular Aspects of Virus and Host Interactions in Pathogenesis of Adult T cell Leukemia/Lymphoma (ATL)

    The study of tumor viruses paves the way for understanding the mechanisms of virus pathogenesis, including those involved in establishing infection and dissemination in the host tumor affecting immune-compromised patients. The processes ranging from viral infection to progressing malignancy are slow and usually insufficient for establishment of transformed cells that develop cancer in only ...

No Evidence of HTLV-II Infection Among Immonoblot Indeterminate Samples Using Nested PCR in Mashhad, Northeast of Iran

A Systematic Review for Estimation of HTLV-I Infection in the Blood Donors of Iran